About Me

Louis

Bioinformatics & Comp. Bio
HUST & BGI

👋 Hello, I'm Louis.

I am a senior at Huazhong University of Science and Technology (HUST) majoring in Bioinformatics.

My passion lies in decoding the “Language of Life” through computational approaches and single-cell analysis. This blog serves as my digital garden where I cultivate knowledge, document workflows, and share slices of my life.

Research Focus
  • Single-cell & Spatial Omics
  • Comparative Genomics
  • AI for Science (Biology)
  • Mathematical Modeling

Please check my recent posts for details.

Tech Stack
Python R Bash Linux
scRNA-seq Stereo-seq ML Git/Docker

🧪 Research Experience

🐦 Heterogeneity Between Bird Retinas (Ongoing)

Role: Intern @ BGI & Graduation Thesis

Investigating cellular heterogeneity in avian visual systems using spatial transcriptomics.

  • Stereo-seq Analysis: Processing high-resolution spatial transcriptomics data.
  • Image Processing: Implemented cell segmentation and registration algorithms.
  • Network Analysis: Constructing Cell-Cell Communication networks to understand unique pathways.

🧬 Genomic Evolution Analysis

Role: Intern @ BGI

Participated in a large-scale primate genome evolution project.

  • Performed variant filtering and phylogenetic tree reconstruction.
  • Handled TB-level genomic data on Linux HPC clusters.

🧫 Lactic Acid Bacteria Genomics

Explored the genomic features of multiple bacterial strains.

  • Constructed gene copy-number matrices.
  • Applied Random Forest models to identify phylogenetically informative marker genes.
  • Analyzed correlation between genomic features and ANI-based distances.

🎓 Looking Forward

I plan to pursue graduate studies in Computational Biology / Bioinformatics.
My goal is to leverage cutting-edge algorithms to solve complex biological puzzles.

"Life is like a camera, focus on what is important."

If you find this blog useful, that is my greatest meaningful reward.